SCHEMBL14452016

SCHEMBL14452016

CCN(CCNS(C)(=O)=O)c1ccc(NC(=O)NS(=O)(=O)c2cc(OC)ccc2OC)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.46
LMNA P02545 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
HTT P42858 2/20 0.46
HSD17B10 Q99714 2/20 0.46
L3MBTL3 Q96JM7 1/20 0.46
ALDH1A1 P00352 5/20 0.45
MAPK1 P28482 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
GFER P55789 1/20 0.45
TP53 P04637 1/20 0.45
GAA P10253 2/20 0.43
KDM4E B2RXH2 1/20 0.43
NPC1 O15118 1/20 0.40
ALOX15 P16050 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14452015 0.90 MAPT (0.55) MAPTLMNASMN1; SMN2HTTHSD17B10
SCHEMBL14452017 0.90 MAPT (0.48) MAPTLMNASMN1; SMN2HTTHSD17B10
SCHEMBL14452018 0.84 MAPT (0.55) MAPTLMNASMN1; SMN2HTTHSD17B10
SCHEMBL14470199 0.81 MAPT (0.46) MAPTLMNASMN1; SMN2HTTHSD17B10
SCHEMBL14470193 0.79 GAA (0.47) MAPTLMNASMN1; SMN2HTTHSD17B10
SCHEMBL14514586 0.79 MAPT (0.48) MAPTSMN1; SMN2L3MBTL3ALDH1A1MAPK1
SCHEMBL11739547 0.76 POLB (0.52) MAPTLMNASMN1; SMN2HTTHSD17B10
SCHEMBL13741630 0.75 ALDH1A1 (0.44) MAPTLMNASMN1; SMN2HTTHSD17B10
SCHEMBL9818478 0.74 MAPT (0.48) MAPTLMNASMN1; SMN2HTTHSD17B10
SCHEMBL8597482 0.73 MAPT (0.48) MAPTLMNASMN1; SMN2HTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7250249-B2 Black and white photothermographic material FUJIFILM CORPORATION (JP) 2007-07-31 US disclosed
US-7247421-B2 Image forming method using photothermographic material FUJIFILM CORPORATION (JP) 2007-07-24 US disclosed