Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL28495094 | 1.00 | TSHR (0.90) | — | |
| Maleic Acid SCHEMBL1208678 | 1.00 | — | — | |
| Fumaric Acid SCHEMBL144528 | 1.00 | — | — | |
| Maleic Acid SCHEMBL28010119 | 0.95 | TSHR (0.82) | — | |
| Maleic Acid SCHEMBL27558805 | 0.95 | TSHR (0.82) | — | |
| Maleic Acid SCHEMBL2046430 | 0.95 | TSHR (1.00) | — | |
| Fumaric Acid SCHEMBL3998225 | 0.95 | — | — | |
| Maleic Acid SCHEMBL20487516 | 0.95 | TSHR (1.00) | — | |
| Fumaric Acid SCHEMBL2046433 | 0.95 | TSHR (1.00) | — | |
| Fumaric Acid SCHEMBL6875 | 0.95 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3694627-B1 | METAL ORGANIC FRAMEWORK BASED WATER CAPTURE APPARATUS | COMMW SCIENT IND RES ORG (AU) | 2025-11-26 | — | — | EP | claimed |
| US-12472483-B2 | Sorbent materials and water harvesting devices including the same | THE JOHNS HOPKINS UNIVERSITY (US) | 2025-11-18 | — | — | US | claimed |
| CN-120132805-A | Glass fiber-based molecular sieve/aluminum fumaric acid MOF composite adsorbent and synthetic method and application thereof | 江苏嘉盛环境设备制造有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-120114961-A | Porous MOFs runner device grown in situ on glass fiber runner and preparation method and application thereof | 广东碳语新材料有限公司 | 2025-06-10 | — | — | CN | claimed |
| WO-2025110879-A1 | SORPTION-ENHANCED COMPRESSED AIR STORAGE | WILGENHAEGE INVESTMENTS B.V. (NL) | 2025-05-30 | — | — | WO | claimed |
| WO-2025090627-A1 | COMPOSITIONS, SYSTEMS, AND METHODS FOR WATER AND WATER VAPOR UPTAKE | Transaera, Inc. (US) | 2025-05-01 | — | — | WO | claimed |
| WO-2025063302-A1 | ORGANIC METAL STRUCTURE, METHOD FOR PRODUCING SAME, GAS ADSORPTION MATERIAL USING SAME, AND METHOD FOR PRODUCING GAS ADSORPTION MATERIAL | ユーゼオ株式会社 | 2025-03-27 | — | — | WO | claimed |
| US-12201939-B2 | Metal-organic framework (MOF) materials for superior refrigerant drying performance | PARKER-HANNIFIN CORPORATION (US) | 2025-01-21 | — | — | US | claimed |
| US-20240252974-A1 | Heat Pump-Based Water Harvesting Systems, And Methods Of Using Thereof | Water Harvesting, Inc. (US) | 2024-08-01 | — | — | US | claimed |
| US-20240209397-A1 | Thermally Stable Lipid-Nucleic Acid Molecule Formulations Utilising Metal Organic Framework (MOF) Shells | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 2024-06-27 | — | — | US | claimed |
| US-20140305803-A1 | PRETREATMENT COMPOSITIONS AND METHODS FOR COATING A METAL SUBSTRATE | PPG IND OHIO INC (US) | 2014-10-16 | — | — | US | claimed |
| US-20120183806-A1 | Pretreatment Compositions and Methods For Coating A Metal Substrate | PPG INDUSTRIES, INC. (US) | 2012-07-19 | — | — | US | claimed |
| US-20080035580-A1 | Methods and Compositions for Treatment of Water | SPECIAL WATER PATENTS B.V. (NL) | 2008-02-14 | — | — | US | claimed |
| CN-1718699-A | Catalytic combustion adjuvant for coal | YIN XIAOLIN (CN) | 2006-01-11 | — | — | CN | claimed |
| US-6764612-B2 | Encapsulated peroxide compositions | GEO SPECIALTY CHEMICALS, INC. | 2004-07-20 | — | — | US | claimed |
| US-6699403-B2 | ORGANIC PEROXIDE ENTRAINED IN PRECIPITATED METALLIC SOAP | GEO SPECIALTY CHEMICALS, INC. | 2004-03-02 | — | — | US | claimed |
| WO-2003082734-A1 | SUPPORTED PEROXIDE COMPOSITIONS | GEO SPECIALTY CHEMICALS, INC. (US) | 2003-10-09 | — | — | WO | claimed |
| US-20030178600-A1 | Encapsulated peroxide compositions | GEO SPECIALTY CHEMICALS, INC. | 2003-09-25 | — | — | US | claimed |
| US-20030178599-A1 | Supported peroxides | GEO SPECIALTY CHEMICALS, INC. | 2003-09-25 | — | — | US | claimed |
| US-5411731-A | Gentle, refreshing feel | KAO CORPORATION (JP) | 1995-05-02 | — | — | US | claimed |