SCHEMBL14706832

SCHEMBL14706832

C[n+]1c(C=Cc2cc3c4c(c2)CCCN4CCC3)sc2cc(S(=O)(=O)N3CCCCC3)ccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SNCA P37840 1/20 0.48
▸ TP53 P04637 2/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ MAPT P10636 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ VDR P11473 1/20 0.39
▸ GFER P55789 1/20 0.39
▸ GPR55 Q9Y2T6 1/20 0.39
▸ RAB9A P51151 2/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ TSHR P16473 3/20 0.37
▸ MCOLN3 Q8TDD5 2/20 0.37
▸ LMNA P02545 2/20 0.37
▸ NPSR1 Q6W5P4 2/20 0.37
▸ THRB P10828 1/20 0.37
▸ POLB P06746 2/20 0.37
▸ INSR P06213 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1105806 1.00 SNCA (0.48) SNCATP53ALDH1A1MAPTHPGD
SCHEMBL14747438 0.82 ALDH1A1 (0.46) ALDH1A1MAPTHPGDVDRGFER
SCHEMBL13194374 0.81 SNCA (0.64) SNCAMAPTRAB9ANPSR1THRB
SCHEMBL14454740 0.81 SNCA (0.64) SNCAMAPTRAB9ANPSR1THRB
SCHEMBL1105734 0.78 CYP2C9 (0.42) SNCATP53ALDH1A1LMNAL3MBTL1
SCHEMBL14747445 0.78 TP53 (0.42) SNCATP53ALDH1A1HPGDLMNA
SCHEMBL14708648 0.77 ALDH1A1 (0.54) TP53ALDH1A1MAPTHPGDVDR
SCHEMBL1105637 0.74 BCHE (0.48) SNCAALDH1A1MAPTHPGDTSHR
SCHEMBL1105805 0.73 ALDH1A1 (0.50) ALDH1A1MAPTHPGDVDRGFER
SCHEMBL1105639 0.71 CYP1A2 (0.53) ALDH1A1MAPTHPGDVDRGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8759526-B2 Dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes—useful or detection or quantification of desirable target molecules ENZO LIFE SCIENCES, INC. (US) 2014-06-24 — — US disclosed
US-20130045480-A1 Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2013-02-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045480-A1 Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules ANXA5, DCLRE1B, ANXA4 SNCA 3372/4885TP53 1009/4885ALDH1A1 3717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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