Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.35 |
| ▸ | CRBN known ✓ | Q96SW2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30019344 | 1.00 | MAPK1 (0.39) | MAPK1NNMTHCAR3MGLLKDM4E | |
| SCHEMBL1445644 | 0.99 | MAPK1 (0.40) | MAPK1NNMTHCAR3MGLLKDM4E | |
| SCHEMBL30914672 | 0.99 | MAPK1 (0.40) | MAPK1NNMTHCAR3MGLLKDM4E | |
| Acetone SCHEMBL1019109 | 0.95 | MAPK1 (0.40) | MAPK1NNMTHCAR3MGLLKDM4E | |
| Acetone SCHEMBL17732269 | 0.93 | MAPK1 (0.39) | MAPK1NNMTHCAR3MGLLKDM4E | |
| SCHEMBL28248952 | 0.90 | NNMT (0.38) | MAPK1NNMTHCAR3KDM4EGAA | |
| Hydrochloric Acid SCHEMBL5087052 | 0.87 | MAPK1 (0.40) | MAPK1NNMTHCAR3MGLLKDM4E | |
| SCHEMBL1509187 | 0.86 | MAPK1 (0.41) | MAPK1NNMTHCAR3MGLLKDM4E | |
| SCHEMBL16938414 | 0.81 | GABRP (0.49) | MAPK1NNMTMGLLKDM4EGAA | |
| SCHEMBL14603527 | 0.81 | HCAR3 (0.38) | MAPK1NNMTHCAR3MGLLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4667019-A1 | PSMA-TARGETED RADIOPHARMACEUTICAL, AND SYNTHESIS AND USE THEREOF | Norroy Bioscience Co., Ltd. (CN) | 2025-12-24 | — | — | EP | claimed |
| CN-118496305-A | PSMA targeted radiopharmaceuticals, synthesis and uses thereof | 无锡诺宇医药科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-118496299-A | PSMA targeted radioactive diagnosis and treatment integrated medicine and synthesis and application thereof | 无锡诺宇医药科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-117883585-A | Medicine for targeting fibroblast activation protein and application thereof | 无锡诺宇医药科技有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117186087-A | Carbonic anhydrase IX targeted radioactive diagnosis and treatment medicine and preparation method thereof | 无锡诺宇医药科技有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-112029905-B | Gene chip and kit for detecting TORCH pathogen | 珠海赛乐奇生物技术股份有限公司 | 2023-08-11 | — | — | CN | claimed |
| WO-2021042884-A1 | PROBES, GENE CHIP AND KIT FOR DETECTING FOLIC ACID GENE POLYMORPHISM | 珠海赛乐奇生物技术股份有限公司 | 2021-03-11 | — | — | WO | claimed |
| WO-2012155055-A9 | INTEGRIN-TARGETED IMAGING OF INFLAMMATION IN VASCULAR REMODELING | YALE UNIVERSITY (US) | 2013-09-19 | — | — | WO | claimed |
| WO-2012155055-A2 | INTEGRIN-TARGETED IMAGING OF INFLAMMATION IN VASCULAR REMODELING | YALE UNIVERSITY (US) | 2012-11-15 | — | — | WO | claimed |
| US-6217845-B1 | IMAGING; THERAPY | ANORMED, INC. (CA) | 2001-04-17 | — | — | US | claimed |
| EP-0384769-B1 | Protein labelling | JOHNSON MATTHEY PLC (GB) | 1996-04-24 | — | — | EP | claimed |
| EP-0384769-A2 | Protein labelling | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-4667019-A1 | PSMA-TARGETED RADIOPHARMACEUTICAL, AND SYNTHESIS AND USE THEREOF | Norroy Bioscience Co., Ltd. (CN) | 2025-12-24 | — | — | EP | disclosed |
| CN-118126024-B | Brand-new skeleton 99mTc-FAPI diagnostic probe and application thereof in preparation of tumor diagnosis drugs or reagents | 中国药科大学 | 2024-08-23 | — | — | CN | disclosed |
| WO-2024169037-A1 | PSMA-TARGETED RADIOPHARMACEUTICAL, AND SYNTHESIS AND USE THEREOF | 无锡诺宇医药科技有限公司 | 2024-08-22 | — | — | WO | disclosed |
| WO-2024169886-A1 | PSMA TARGETED RADIOACTIVE DRUG FOR INTEGRATED DIAGNOSIS AND TREATMENT, AND SYNTHESIS AND USE THEREOF | 无锡诺宇医药科技有限公司 | 2024-08-22 | — | — | WO | disclosed |
| EP-0384769-B1 | Protein labelling | JOHNSON MATTHEY PLC (GB) | 1996-04-24 | — | — | EP | disclosed |
| US-5420285-A | Imaging for medicine | JOHNSON MATTHEY, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5206370-A | Certain pyridyl hydrazines and hydrazides useful for protein labeling | JOHNSON MATTHEY, INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0384769-A2 | Protein labelling | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1990-08-29 | — | — | EP | disclosed |