Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456685 | 0.81 | ALDH1A1 (0.57) | KMT2AMEN1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL14456744 | 0.80 | KMT2A (0.56) | KMT2AMEN1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL14456909 | 0.79 | CYP3A4 (0.53) | KMT2AMEN1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL14456681 | 0.79 | KMT2A (0.52) | KMT2AMEN1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL8228144 | 0.78 | KMT2A (0.54) | KMT2AMEN1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL8230258 | 0.78 | TSHR (0.49) | KMT2AMEN1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL8223229 | 0.77 | TBK1 (0.51) | KMT2AMEN1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL8223139 | 0.77 | TSHR (0.48) | KMT2AMEN1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL14456706 | 0.75 | TSHR (0.48) | KMT2AMEN1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL14456691 | 0.75 | TSHR (0.48) | KMT2AMEN1TSHRSMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |