Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469551 | 0.90 | KDM4E (0.48) | RAB9AALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL14469466 | 0.88 | MEN1 (0.39) | RAB9AALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL14469554 | 0.85 | SMN1; SMN2 (0.40) | RAB9AALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL14469560 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4ESMN1; SMN2HTT | |
| SCHEMBL14469569 | 0.83 | ALDH1A1 (0.47) | RAB9AALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL14469451 | 0.82 | TSHR (0.46) | RAB9AALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL14469552 | 0.82 | ALDH1A1 (0.49) | RAB9AALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL14469473 | 0.81 | KMT2A (0.43) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL14469461 | 0.81 | HDAC1 (0.46) | KDM4ESMN1; SMN2MEN1KMT2AALOX15 | |
| SCHEMBL14469113 | 0.80 | ALDH1A1 (0.46) | RAB9AALDH1A1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |