Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | LSS | P48449 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456956 | 0.90 | CNR1 (0.69) | POLBLSSALDH1A1TSHRLMNA | |
| SCHEMBL14456748 | 0.86 | KMT2A (0.73) | POLBALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL14456892 | 0.83 | MEN1 (0.63) | ALDH1A1TSHRKMT2ACYP3A4CYP2D6 | |
| SCHEMBL14456786 | 0.82 | MEN1 (0.63) | POLBALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL14456954 | 0.81 | ALDH1A1 (0.55) | POLBALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL14456960 | 0.81 | CHRM1 (0.62) | CYP3A4 | |
| SCHEMBL13591254 | 0.81 | MEN1 (0.65) | POLBALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL14456827 | 0.81 | CYP3A4 (0.68) | POLBALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL14456959 | 0.80 | ALDH1A1 (0.65) | ALDH1A1TSHRLMNAKMT2AUSP2 | |
| SCHEMBL14456713 | 0.80 | POLB (0.84) | POLBALDH1A1TSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |