Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | PRKCG | P05129 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PRKCB | P05771 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | PRKACG | P22612 | 1/20 | 0.53 |
| ▸ | PRKACB | P22694 | 1/20 | 0.53 |
| ▸ | PRKCH | P24723 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.53 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456959 | 0.86 | ALDH1A1 (0.65) | KDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14456957 | 0.84 | TGM2 (0.50) | CNR1CYP3A4 | |
| SCHEMBL14469195 | 0.82 | CHRM1 (0.53) | CHRM1CNR1ROCK2ROCK1 | |
| SCHEMBL10983794 | 0.82 | P2RX7 (0.64) | ROCK2P2RX7KDM4EPRKD3PRKCG | |
| SCHEMBL14456952 | 0.81 | POLB (0.78) | CYP3A4 | |
| SCHEMBL14456950 | 0.80 | CYP2C19 (0.60) | CHRM1CYP3A4CYP2C19 | |
| SCHEMBL6792039 | 0.79 | LSS (0.70) | CHRM1CNR1 | |
| SCHEMBL14456956 | 0.78 | CNR1 (0.69) | CNR1 | |
| SCHEMBL14456892 | 0.78 | MEN1 (0.63) | CYP3A4 | |
| SCHEMBL15101977 | 0.77 | CHRM1 (1.00) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |