SCHEMBL1445778

SCHEMBL1445778

Cc1cccc(-c2ccnnn2)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.43
NUDT1 P36639 5/20 0.40
P2RX7 Q99572 2/20 0.39
TLR8 Q9NR97 1/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TRPA1 O75762 1/20 0.33
ATM Q13315 1/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
CDC7 O00311 1/20 0.33
PLK4 O00444 1/20 0.33
MAPK13 O15264 1/20 0.33
PDPK1 O15530 1/20 0.33
DAPK3 O43293 1/20 0.33
DYRK3 O43781 1/20 0.33
JAK2 O60674 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resorcinol SCHEMBL1244732 0.89 CNR2 (0.37) CNR2NUDT1P2RX7TRPA1ATM
SCHEMBL7913045 0.85 NPC1 (0.44) CNR2NPC1RAB9ASMN1; SMN2ATM
SCHEMBL27208074 0.78 CNR2 (0.40) CNR2NUDT1P2RX7TLR8NPC1
SCHEMBL16731967 0.78 ALDH1A1 (0.32) NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL12483491 0.74 ACHE (0.46) NPC1RAB9ASMN1; SMN2CASP3MAPK1
SCHEMBL12484088 0.71 POLB (0.35) NPC1RAB9ASMN1; SMN2FGFR1ALDH1A1
SCHEMBL28338023 0.71 TRPA1 (0.44) NPC1RAB9ASMN1; SMN2TRPA1ATM
SCHEMBL27732755 0.70 NUDT1 (0.40) CNR2NUDT1MAP4K4CDK2FRK
SCHEMBL1534219 0.70 HPGD (0.39) SMN1; SMN2TRPA1CDK2MAPK1PARP1
SCHEMBL3086671 0.70 HTR2C (0.44) NPC1SMN1; SMN2MAPK1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8216357-B2 Protective coating compositions and devices GENERAL ELECTRIC COMPANY (US) 2012-07-10 US disclosed
US-20110073171-A1 PROTECTIVE COATING COMPOSITIONS AND DEVICES GENERAL ELECTRIC COMPANY (US) 2011-03-31 US disclosed
EP-2302006-A1 Protective coating compositions and devices General Electric Company (US) 2011-03-30 EP disclosed
CN-100497321-C Process for isolation of monophenolic-bisaryl triazines CYTEC TECH CORP (US) 2009-06-10 CN disclosed
CN-1547573-A Process for isolation of monophenolic-bisaryl triazines CYTEC 2004-11-17 CN disclosed
EP-1397352-A2 PROCESS FOR ISOLATION OF MONOPHENOLIC-BISARYL TRIAZINES Cytec Technology Corp. (US) 2004-03-17 EP disclosed
WO-2003000667-A2 PROCESS FOR ISOLATION OF MONOPHENOLIC-BISARYL TRIAZINES CYTEC TECHNOLOGY CORP. (US) 2003-01-03 WO disclosed