Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 2/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889322 | 0.96 | GRIN2B (0.49) | GRIN2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4148437 | 0.96 | GRIN2B (0.49) | GRIN2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14458017 | 0.85 | AR (0.43) | GRIN2BL3MBTL1DDB1CRBN | |
| SCHEMBL14474703 | 0.83 | PDE4A (0.40) | GRIN2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13945021 | 0.83 | PDE4A (0.40) | GRIN2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7045469 | 0.81 | DRD2 (0.43) | GRIN2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3495660 | 0.81 | DRD2 (0.43) | GRIN2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22190351 | 0.79 | PARP1 (0.48) | PDE4APDE4BPDE4CPDE4DCMA1 | |
| SCHEMBL22201144 | 0.79 | PARP1 (0.48) | PDE4APDE4BPDE4CPDE4DCMA1 | |
| SCHEMBL3657517 | 0.79 | CRBN (0.58) | PDE4APDE4BPDE4CPDE4DKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |
| US-20040147764-A1 | Method for production of delta 1-pyrrolines | BAYER CROPSCIENCE AG (DE) | 2004-07-29 | — | — | US | disclosed |
| EP-1379500-A2 | METHOD FOR THE PRODUCTION OF $g(D)?1 PYRROLINES | Bayer CropScience AG (DE) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002081442-A2 | METHOD FOR THE PRODUCTION OF Δ1 PYRROLINES | BAYER CROPSCIENCE AG (DE) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147764-A1 | Method for production of delta 1-pyrrolines | AR, NR5A1, SRD5A1 | GRIN2B 845/4885PDE4A 1765/4885PDE4B 1989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.