Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718585 | 0.80 | THRB (0.37) | THRBCA9GRM5PKMHPGD | |
| SCHEMBL12647208 | 0.80 | GRM5 (0.53) | THRBGRM5PKMHPGDSMN1; SMN2 | |
| SCHEMBL5657033 | 0.79 | ALDH1A1 (0.43) | THRBCA9HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL17706530 | 0.78 | THRB (0.35) | THRBCA9GRM5PKMHPGD | |
| SCHEMBL721848 | 0.78 | ALDH1A1 (0.42) | THRBCA9GRM5PKMHPGD | |
| SCHEMBL20631742 | 0.75 | PRKCI (0.44) | IKBKBALDH1A1GAAMAPTPRKCI | |
| SCHEMBL14458102 | 0.75 | POLB (0.44) | HPGDALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL25309343 | 0.72 | KDM4E (0.46) | CA9HPGDSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4798197 | 0.72 | FTO (0.59) | HPGDSMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL1798438 | 0.71 | ESR1 (0.33) | THRBPKMHPGDIKBKBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250389-B1 | Antifungal compound and process for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-07-31 | — | — | US | disclosed |
| US-7250389-B1 | Antifungal compound and process for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-07-31 | — | — | US | disclosed |