Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA7 | P43166 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SELL | P14151 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31645569 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2KDM4ECA1 | |
| SCHEMBL1520617 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2KDM4ECA1 | |
| SCHEMBL14458093 | 0.79 | THRB (0.38) | ALDH1A1MAPTSMN1; SMN2KDM4ECA9 | |
| SCHEMBL595464 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2KDM4ECA1 | |
| SCHEMBL8834235 | 0.79 | KDM4E (0.50) | ALDH1A1MAPTSMN1; SMN2KDM4ECA1 | |
| SCHEMBL29621628 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2KDM4ECA1 | |
| SCHEMBL31646044 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2KDM4ECA1 | |
| SCHEMBL31193135 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2KDM4ECA1 | |
| SCHEMBL1759159 | 0.77 | GRM5 (0.53) | ALDH1A1MAPTSMN1; SMN2KDM4ECA1 | |
| SCHEMBL1186851 | 0.77 | GABRP (0.47) | ALDH1A1MAPTSMN1; SMN2KDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250389-B1 | Antifungal compound and process for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-07-31 | — | — | US | disclosed |
| EP-1054011-B1 | NOVEL ANTIFUNGAL COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA (JP) | 2006-09-13 | — | — | EP | disclosed |
| EP-1054011-A1 | NOVEL ANTIFUNGAL COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| EP-0504818-B1 | Microbiological process for the preparation of 6-hydroxy picolinic acid | LONZA AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| EP-0498316-B1 | Microbiological process for the production of 6-hydroxypicolinic acid | LONZA AG (CH) | 1995-09-06 | — | — | EP | disclosed |
| US-5270203-A | Biologically pure culture of Alcaligenes faecalis DSM 6335 | LONZA LTD. (CH) | 1993-12-14 | — | — | US | disclosed |
| US-5268294-A | Mutants | LONZA LTD. (CH) | 1993-12-07 | — | — | US | disclosed |
| US-5264361-A | Biosynthesis, alcalgenes | LONZA LTD. (CH) | 1993-11-23 | — | — | US | disclosed |
| US-5238830-A | Cultivating aerobic biomass with picolinic acid or soluble salt and mineral acid, hydroxylating with biomass | LONZA LTD. (CH) | 1993-08-24 | — | — | US | disclosed |
| US-5182197-A | Alcaligenes | LONZA LTD. (CH) | 1993-01-26 | — | — | US | disclosed |
| EP-0504818-A2 | Microbiological process for the preparation of 6-hydroxy picolinic acid | LONZA AG (CH) | 1992-09-23 | — | — | EP | disclosed |
| EP-0498316-A1 | Microbiological process for the production of 6-hydroxypicolinic acid | LONZA AG (CH) | 1992-08-12 | — | — | EP | disclosed |