Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12298161 | 0.92 | PIM1 (0.62) | PIM1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12298170 | 0.86 | MAPT (0.54) | PIM1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4239559 | 0.85 | PLAU (0.52) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4057215 | 0.83 | CYP1A2 (0.54) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4243912 | 0.83 | MEN1 (0.52) | PIM1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4239248 | 0.82 | CFTR (0.56) | PIM1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL12298158 | 0.81 | VCP (0.53) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL12297751 | 0.81 | CFTR (0.46) | PIM1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4065329 | 0.81 | PKM (0.47) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4242424 | 0.80 | ALOX5 (0.54) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244739-B2 | Compounds and uses thereof in modulating amyloid beta | TORREYPINES THERAPEUTICS, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244739-B2 | Compounds and uses thereof in modulating amyloid beta | TORREYPINES THERAPEUTICS, INC. (US) | 2007-07-17 | — | — | US | disclosed |