Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14460784 | 0.83 | MEN1 (0.37) | DRD2DRD1ALDH1A1MAPTLMNA | |
| SCHEMBL14460821 | 0.79 | MEN1 (0.31) | DRD2DRD1MEN1KMT2A | |
| SCHEMBL14460838 | 0.76 | DRD2 (0.31) | DRD2DRD1MEN1KMT2A | |
| SCHEMBL14460792 | 0.76 | DRD2 (0.31) | DRD2DRD1MEN1KMT2A | |
| SCHEMBL3935230 | 0.75 | RXRA (0.50) | RXRALMNASMN1; SMN2 | |
| SCHEMBL14393191 | 0.74 | MAPT (0.38) | ALDH1A1MAPTBRD4KDM4EMEN1 | |
| SCHEMBL14460615 | 0.74 | MEN1 (0.45) | MAPTBRD4RXRALMNAKDM4E | |
| SCHEMBL6048623 | 0.74 | KCNN4 (0.49) | ALDH1A1KCNN4MAPTEGFRLMNA | |
| SCHEMBL13045159 | 0.73 | MEN1 (0.44) | ALDH1A1MAPTBRD4RXRALMNA | |
| SCHEMBL14460614 | 0.73 | KMT2A (0.44) | ALDH1A1MAPTBRD4RXRALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241714-B2 | Bridged bi-aromatic catalysts, complexes, and methods of using the same | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |