Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 11/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928718 | 0.82 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL14463434 | 0.78 | MAPT (0.47) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL5838060 | 0.77 | MAPK1 (0.62) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL14463550 | 0.73 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11348624 | 0.71 | PTGS2 (0.67) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10647647 | 0.71 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL6655518 | 0.70 | PKM (0.55) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL2772541 | 0.69 | ALDH1A1 (0.67) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL4931104 | 0.68 | MAPT (0.58) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL7499979 | 0.68 | MAPT (0.55) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1810677-A1 | RECEPTOR FUNCTION REGULATING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2007-07-25 | — | — | EP | disclosed |