Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | GPR39 | O43194 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463870 | 0.92 | TRPV1 (0.40) | EPHX2NR1H4TRPC5TRPV1KCNN3 | |
| SCHEMBL14463910 | 0.90 | EPHX2 (0.42) | EPHX2NR1H4TRPC5TRPV1KCNN3 | |
| SCHEMBL14463475 | 0.89 | NPC1 (0.39) | EPHX2NR1H4NPC1RAB9ALMNA | |
| SCHEMBL4931809 | 0.89 | CYP3A4 (0.44) | EPHX2NR1H4TRPC5TRPV1KCNN3 | |
| SCHEMBL14463582 | 0.88 | NPC1 (0.50) | EPHX2NR1H4L3MBTL1NPC1RAB9A | |
| SCHEMBL14463835 | 0.86 | NPC1 (0.41) | EPHX2NR1H4POLBNPC1RAB9A | |
| SCHEMBL14463585 | 0.86 | NPC1 (0.41) | EPHX2NR1H4L3MBTL1NPC1RAB9A | |
| SCHEMBL4922605 | 0.86 | TRPC5 (0.45) | EPHX2NR1H4TRPC5TRPV1KCNN3 | |
| SCHEMBL14463473 | 0.81 | TRPC5 (0.37) | TRPC5NPC1RAB9ATP53CYP3A4 | |
| SCHEMBL4927317 | 0.81 | P2RX3 (0.41) | EPHX2NR1H4TRPC5TRPV1KCNN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1810677-A1 | RECEPTOR FUNCTION REGULATING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2007-07-25 | — | — | EP | disclosed |