Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14464046 | 0.81 | PTP4A3 (0.71) | NAT1MEN1POLBMAPTKMT2A | |
| SCHEMBL14899471 | 0.81 | PTP4A3 (0.75) | NAT1MEN1POLBMAPTKMT2A | |
| SCHEMBL24253263 | 0.80 | NAT1 (0.68) | NAT1MEN1POLBMAPTKMT2A | |
| SCHEMBL4803625 | 0.79 | CA2 (0.73) | NAT1MEN1POLBMAPTKMT2A | |
| SCHEMBL4803620 | 0.79 | CA2 (0.73) | NAT1MEN1POLBMAPTKMT2A | |
| SCHEMBL9573277 | 0.77 | NAT1 (1.00) | NAT1MEN1POLBMAPTKMT2A | |
| SCHEMBL9573270 | 0.77 | NAT1 (1.00) | NAT1MEN1POLBMAPTKMT2A | |
| SCHEMBL14899561 | 0.76 | MYC (0.77) | NAT1MEN1POLBMAPTKMT2A | |
| SCHEMBL14226382 | 0.75 | NAT1 (0.69) | NAT1MEN1POLBMAPTKMT2A | |
| SCHEMBL8167434 | 0.74 | PIM1 (0.75) | NAT1NPC1MYCMAXCISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081091-A1 | RHODANDSE DERIVARIVES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-07-19 | — | — | WO | disclosed |