Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312571 | 0.82 | CYP1A2 (0.59) | MGLLALDH1A1KDM4EHPGDBLM | |
| SCHEMBL10059426 | 0.79 | MGLL (0.44) | MGLLALDH1A1KDM4EHPGDBLM | |
| SCHEMBL10059356 | 0.77 | KDM4E (0.62) | MGLLALDH1A1KDM4EHPGDBLM | |
| SCHEMBL6536599 | 0.77 | CYP1A2 (0.53) | MGLLALDH1A1KDM4EHPGDBLM | |
| Hydronidone SCHEMBL143564 | 0.77 | ALDH1A1 (0.67) | ESR1ESR2MGLLALDH1A1KDM4E | |
| SCHEMBL21249132 | 0.76 | MGLL (0.44) | MGLLALDH1A1KDM4EHPGDBLM | |
| SCHEMBL10079093 | 0.73 | HTT (0.43) | MGLLALDH1A1KDM4EHPGDBLM | |
| SCHEMBL141680 | 0.73 | ESR1 (0.46) | ESR1ESR2MGLLALDH1A1KDM4E | |
| SCHEMBL13263844 | 0.73 | HSP90AA1 (0.39) | ESR1ESR2MGLLALDH1A1KDM4E | |
| SCHEMBL10059398 | 0.72 | MGLL (0.41) | MGLLALDH1A1KDM4EHPGDBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062167-A9 | METHOD OF MODULATING STRESS-ACTIVATED PROTEIN KINASE SYSTEM | INTERMUNE INC (US) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007062167-A2 | METHOD OF MODULATING STRESS-ACTIVATED PROTEIN KINASE SYSTEM | INTERMUNE, INC. (US) | 2007-05-31 | — | — | WO | disclosed |