Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536599 | 0.93 | CYP1A2 (0.53) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL5697621 | 0.87 | CYP1A2 (0.46) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL15964171 | 0.86 | ALDH1A1 (0.56) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL14464201 | 0.82 | ESR1 (0.43) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL23619123 | 0.81 | ALDH1A1 (0.55) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL147797 | 0.81 | KDM4E (0.55) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL3729672 | 0.81 | ALDH1A1 (0.55) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL14194615 | 0.81 | KDM4E (0.55) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL146809 | 0.81 | ALDH1A1 (0.55) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL146271 | 0.81 | ALDH1A1 (0.54) | CYP1A2ALDH1A1KDM4EHPGDBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514348-A2 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | Noetix Pharma LLC (US) | 2025-03-05 | — | — | EP | claimed |
| US-20240299698-A1 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | NOETIX PHARMA LLC | 2024-09-12 | — | — | US | claimed |
| WO-2023211684-A2 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | NOETIX PHARMA LLC (US) | 2023-11-02 | — | — | WO | claimed |
| EP-2262501-B1 | TREATMENT OF SEPSIS WITH 5-ETHYL-1-PHENYL-2(1H)-PYRIDONE | SOLANAN INC (US) | 2014-08-13 | — | — | EP | claimed |
| US-20120071518-A1 | Treatment of Sepsis with 5-Ethyl-1-Phenyl-2(1H)-Pyridone | SOLANAN, INC. (US) | 2012-03-22 | — | — | US | claimed |
| US-8093210-B2 | Treatment of sepsis with 5-ethyl-1-phenyl-2(1H)-pyridone | SOLANAN, INC. (US) | 2012-01-10 | — | — | US | claimed |
| US-20110092549-A1 | Treatment of Sepsis with 5-Ethyl-1-Phenyl-2(1H)-Pyridone | SOLANAN, INC. (US) | 2011-04-21 | — | — | US | claimed |
| EP-2262501-A2 | TREATMENT OF SEPSIS WITH 5-ETHYL-1-PHENYL-2(1H)-PYRIDONE AND NOVEL METHODS FOR SYNTHESIS | Solanan, Inc. (US) | 2010-12-22 | — | — | EP | claimed |
| WO-2009111785-A2 | TREATMENT OF SEPSIS WITH 5-ETHYL-1-PHENYL-2(1H)-PYRIDONE AND NOVEL METHODS FOR SYNTHESIS | SOLANAN, INC. (US) | 2009-09-11 | — | — | WO | claimed |
| EP-0866656-B1 | USE OF N-SUBSTITUTED PYRIDONES AS TUMOR NECROSIS FACTOR ALPHA INHIBITORS | MARGOLIN SOLOMON B (US) | 2007-04-25 | — | — | EP | claimed |
| EP-1242084-B1 | TREATMENT OF BREAST CARCINOMAS, ASTROCYTOMAS, MELANOMAS AND RELATED TUMORS | MARGOLIN SOLOMON B (US) | 2006-07-05 | — | — | EP | claimed |
| EP-1261338-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | CYMAR INC (US) | 2006-06-14 | — | — | EP | claimed |
| US-6956044-B1 | Compositions and methods for treatment of epilepsy | INTERMUNE, INC. | 2005-10-18 | — | — | US | claimed |
| EP-1069898-B1 | TOPICAL ANTISEPTIC COMPOSITIONS AND METHODS | MARGOLIN SOLOMON B (US) | 2004-05-12 | — | — | EP | claimed |
| EP-0813409-B1 | TREATMENT OF CYTOKINE GROWTH FACTOR CAUSED DISORDERS | MARGOLIN SOLOMON B (US) | 2004-05-06 | — | — | EP | claimed |
| EP-0702551-B1 | COMPOSITIONS AND METHODS FOR REPARATION AND PREVENTION OF FIBROTIC LESIONS | MARGOLIN SOLOMON B (US) | 2002-09-25 | — | — | EP | claimed |
| US-5962478-A | ADMINISTERING A N-SUBSTITUTED 2(1H)PYRIDONE | INTERMUNE, INC. | 1999-10-05 | — | — | US | claimed |
| US-20250367178-A1 | AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF | AVALYN PHARMA INC (US) | 2025-12-04 | — | — | US | disclosed |
| US-4042699-A | 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1977-08-16 | — | — | US | disclosed |
| US-3974281-A | ANALGESICS, ANTI-PYRETIC AND ANTI-INFLAMMATORY AGENTS | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299698-A1 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | CHAT, PNPO, PLPBP | CYP1A2 486/4885ALDH1A1 1343/4885KDM4E 3737/4885 |
| US-20120071518-A1 | Treatment of Sepsis with 5-Ethyl-1-Phenyl-2(1H)-Pyridone | SELP, PSPH, PLPBP | CYP1A2 271/4885ALDH1A1 1737/4885KDM4E 1751/4885 |
| US-20250367178-A1 | AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF | PLPBP, PIR, PDXK | CYP1A2 123/4885ALDH1A1 167/4885KDM4E 2879/4885 |
| US-20110092549-A1 | Treatment of Sepsis with 5-Ethyl-1-Phenyl-2(1H)-Pyridone | SELP, PSPH, PLPBP | CYP1A2 271/4885ALDH1A1 1737/4885KDM4E 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.