SCHEMBL1446451

SCHEMBL1446451

NC(=O)c1ccc(C(=O)Nc2ccc(O)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.65
MAPT P10636 1/20 0.65
DEGS1 O15121 3/20 0.64
SNCA P37840 1/20 0.64
NQO2 P16083 2/20 0.61
MEN1 O00255 2/20 0.60
POLB P06746 2/20 0.60
LMNA P02545 1/20 0.60
PKM P14618 1/20 0.60
APEX1 P27695 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
BCAT2 O15382 1/20 0.60
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
KDM4E B2RXH2 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
PEPD P12955 1/20 0.59
F2 P00734 1/20 0.57
PLG P00747 1/20 0.57
PLAU P00749 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13210699 0.92 KMT2A (0.73) KMT2AMAPTMEN1POLBLMNA
SCHEMBL8420639 0.90 DEGS1 (0.75) KMT2ADEGS1SNCANQO2MEN1
SCHEMBL900928 0.90 DEGS1 (0.75) KMT2ADEGS1SNCANQO2MEN1
SCHEMBL899585 0.90 DEGS1 (0.75) KMT2ADEGS1SNCANQO2MEN1
SCHEMBL6125777 0.86 KMT2A (0.67) KMT2AMAPTMEN1POLBLMNA
SCHEMBL3282206 0.85 KMT2A (0.85) KMT2AMAPTSNCAMEN1POLB
Terephthalamide SCHEMBL9363256 0.85 KMT2A (0.85) KMT2AMAPTSNCAMEN1POLB
SCHEMBL3902965 0.85 KMT2A (0.72) KMT2AMAPTMEN1POLBTDP1
SCHEMBL14972618 0.85 KMT2A (0.85) KMT2AMAPTSNCAMEN1POLB
SCHEMBL2587802 0.85 POLB (0.85) KMT2AMAPTDEGS1SNCANQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0670855-A1 NITRO OR NITROSO GROUP TERMINATED MESOGENIC EPOXY RESIN ADDUCTS THE DOW CHEMICAL COMPANY (US) 1995-09-13 EP claimed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
WO-1994012555-A1 NITRO OR NITROSO GROUP TERMINATED MESOGENIC EPOXY RESIN ADDUCTS THE DOW CHEMICAL COMPANY (US) 1994-06-09 WO claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
CN-105646158-A Cyclododecatriene trialdehyde, and preparation and application of related compounds 陶氏环球技术有限责任公司 2016-06-08 CN disclosed
CN-103228694-B Heat curable composition and the thermosetting material prepared by heat curable composition Blue Cube Intellectual Property Co.,Ltd. (US) 2016-04-27 CN disclosed
CN-102958971-B Epoxy polycyclopentadiene compounds DOW GLOBAL TECHNOLOGIES INC 2014-12-31 CN disclosed
CN-102037086-B Epoxy resin reactive diluent composition DOW WOLFF CELLULOSICS GMBH 2013-08-28 CN disclosed
CN-102958971-A Epoxy polycyclopentadiene compounds DOW GLOBAL TECHNOLOGIES LLC 2013-03-06 CN disclosed
CN-102666638-A Composite compositions DOW GLOBAL TECHNOLOGIES INC 2012-09-12 CN disclosed
CN-102648247-A coating composition DOW GLOBAL TECHNOLOGIES INC 2012-08-22 CN disclosed
CN-102648227-A Epoxy resin compositions DOW GLOBAL TECHNOLOGIES INC 2012-08-22 CN disclosed
EP-0950649-B1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides MITSUI CHEMICALS INC (JP) 2003-03-26 EP disclosed
US-6130346-A ESTERIFICATION, CARBONATION, SULFONATION, ETHERIFICATION MITSUI CHEMICALS, INC. (JP) 2000-10-10 US disclosed
EP-0950649-A1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides Mitsui Chemicals, Inc. (JP) 1999-10-20 EP disclosed
EP-0670855-A1 NITRO OR NITROSO GROUP TERMINATED MESOGENIC EPOXY RESIN ADDUCTS THE DOW CHEMICAL COMPANY (US) 1995-09-13 EP disclosed
WO-1994025501-A1 EPOXY RESINS CONTAINING THIADIAZOLE AND/OR OXADIAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1994-11-10 WO disclosed
WO-1994012555-A1 NITRO OR NITROSO GROUP TERMINATED MESOGENIC EPOXY RESIN ADDUCTS THE DOW CHEMICAL COMPANY (US) 1994-06-09 WO disclosed
EP-0579743-A1 DIAMINO-ALPHA-ALKYLSTILBENES THE DOW CHEMICAL COMPANY (US) 1994-01-26 EP disclosed
US-5218062-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1993-06-08 US disclosed