SCHEMBL14465481

SCHEMBL14465481

CN(c1ccc(-c2ccccc2)cc1)c1ccc2c(c1)c1ccccc1n2C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.48
KDM4E B2RXH2 3/20 0.48
MAPT P10636 4/20 0.46
HPGD P15428 4/20 0.46
HSD17B10 Q99714 3/20 0.46
ALDH1A1 P00352 3/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
HTT P42858 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PABPC1 P11940 1/20 0.46
LMNA P02545 3/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
TSPO P30536 1/20 0.41
KIF11 P52732 1/20 0.39
NPY5R Q15761 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279539 0.92 GPR3 (0.53) GPR3KDM4EMAPTHPGDHSD17B10
SCHEMBL14465488 0.91 GPR3 (0.46) GPR3KDM4EMAPTHPGDHSD17B10
SCHEMBL18566250 0.91 GPR3 (0.48) GPR3KDM4EMAPTHPGDHSD17B10
SCHEMBL23108693 0.91 GPR3 (0.59) GPR3KDM4EMAPTHPGDHSD17B10
SCHEMBL14465390 0.86 GPR3 (0.50) GPR3KDM4EMAPTHPGDHSD17B10
SCHEMBL279231 0.85 L3MBTL1 (0.51) KDM4EMAPTHPGDALDH1A1KMT2A
SCHEMBL19735334 0.85 L3MBTL1 (0.47) KDM4EMAPTHPGDALDH1A1KMT2A
SCHEMBL12249697 0.85 GPR3 (0.48) GPR3KDM4EMAPTHPGDHSD17B10
SCHEMBL18564772 0.85 GPR3 (0.48) GPR3KDM4EMAPTHPGDHSD17B10
SCHEMBL18566260 0.85 MAPT (0.44) GPR3KDM4EMAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9048436-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-02 US disclosed
US-9048436-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-02 US disclosed
EP-1976838-B1 OXADIAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING THE OXADIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2015-02-25 EP disclosed
US-20140299822-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-09 US disclosed
US-20140299822-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-09 US disclosed
US-20130200344-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-08-08 US disclosed
US-20130200344-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-08-08 US disclosed
US-8389735-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-05 US disclosed
US-8389735-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-05 US disclosed
WO-2007074893-A1 OXADIAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING THE OXADIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-07-05 WO disclosed
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-06-28 US disclosed
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative OXA1L, ADRA1D, CRY1 GPR3 43/4885KDM4E 4218/4885MAPT 3287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.