Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469114 | 0.90 | RAB9A (0.41) | KDM4EALDH1A1HTTRAB9AALOX15 | |
| SCHEMBL14469552 | 0.90 | ALDH1A1 (0.49) | KDM4EALDH1A1HTTRAB9AALOX15 | |
| SCHEMBL14469466 | 0.89 | MEN1 (0.39) | KDM4EALDH1A1RAB9AALOX15SMN1; SMN2 | |
| SCHEMBL14469560 | 0.88 | ALDH1A1 (0.47) | KDM4EALDH1A1HTTALOX15LMNA | |
| SCHEMBL14469479 | 0.88 | CCR5 (0.52) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL14469113 | 0.88 | ALDH1A1 (0.46) | KDM4EALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL14469569 | 0.87 | ALDH1A1 (0.47) | KDM4EALDH1A1RAB9AALOX15SMN1; SMN2 | |
| SCHEMBL14469554 | 0.87 | SMN1; SMN2 (0.40) | KDM4EALDH1A1RAB9AALOX15SMN1; SMN2 | |
| SCHEMBL14469451 | 0.86 | TSHR (0.46) | KDM4EALDH1A1RAB9AALOX15LMNA | |
| SCHEMBL14469471 | 0.86 | ALDH1A1 (0.48) | KDM4EALDH1A1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |