Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469569 | 0.88 | ALDH1A1 (0.47) | FAAHMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL14469560 | 0.87 | ALDH1A1 (0.47) | ACHEMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL14469451 | 0.87 | TSHR (0.46) | FAAHMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL14469473 | 0.86 | KMT2A (0.43) | MEN1KMT2ASMN1; SMN2TSHRALOX15 | |
| SCHEMBL14469552 | 0.85 | ALDH1A1 (0.49) | MEN1KMT2AOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL14469570 | 0.85 | CYP2D6 (0.52) | ACHEMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL14469477 | 0.85 | KMT2A (0.58) | MEN1KMT2ASMN1; SMN2TSHRALOX15 | |
| SCHEMBL14469551 | 0.85 | KDM4E (0.48) | MEN1KMT2ASMN1; SMN2ALOX15KDM4E | |
| SCHEMBL14469457 | 0.83 | FAAH (0.49) | FAAHMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL14469466 | 0.82 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |