Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | FABP6 | P51161 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469569 | 0.90 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL14469451 | 0.89 | TSHR (0.46) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL14469167 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KMT2AACHEMEN1KDM4E | |
| SCHEMBL14469551 | 0.88 | KDM4E (0.48) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL14469473 | 0.88 | KMT2A (0.43) | ALDH1A1KMT2AMEN1KDM4ERORC | |
| SCHEMBL14469461 | 0.87 | HDAC1 (0.46) | KMT2AACHEMEN1KDM4ETSHR | |
| SCHEMBL14469477 | 0.86 | KMT2A (0.58) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL14469466 | 0.84 | MEN1 (0.39) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL14469114 | 0.84 | RAB9A (0.41) | ALDH1A1KMT2AMEN1KDM4ERORC | |
| SCHEMBL14469552 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |