Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469186 | 0.92 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1ACHEKDM4E | |
| SCHEMBL14469298 | 0.91 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL14469188 | 0.89 | ALDH1A1 (0.46) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL14469170 | 0.87 | KDM4E (0.48) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL14469633 | 0.85 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1CYP3A4ACHE | |
| SCHEMBL14469365 | 0.84 | KDM4E (0.48) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL14469256 | 0.83 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1ACHEKDM4E | |
| SCHEMBL14469577 | 0.83 | KDM4E (0.43) | MEN1KMT2ANPC1ALDH1A1KDM4E | |
| SCHEMBL14469573 | 0.81 | MTNR1B (0.39) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL14469292 | 0.81 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |