Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469477 | 0.91 | KMT2A (0.58) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL14469460 | 0.86 | KMT2A (0.51) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL14469556 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL14469558 | 0.84 | ALDH1A1 (0.48) | ALDH1A1USP2KDM4E | |
| SCHEMBL14469456 | 0.83 | SMN1; SMN2 (0.50) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL14469473 | 0.83 | KMT2A (0.43) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL14469464 | 0.83 | MEN1 (0.45) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL14469569 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL14469123 | 0.83 | ADRB2 (0.45) | MEN1KMT2ATSHRKDM4ESMN1; SMN2 | |
| SCHEMBL14469562 | 0.82 | L3MBTL1 (0.47) | ALDH1A1MEN1KMT2ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |