Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469705 | 0.87 | TDP1 (0.42) | PRKCZNPC1RAB9AALDH1A1SLC6A2 | |
| SCHEMBL14469714 | 0.85 | TSHR (0.45) | PRKCZALDH1A1MGLLMMP1MMP12 | |
| SCHEMBL14469745 | 0.82 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL2314407 | 0.70 | HTR2B (0.38) | TDP1SMN1; SMN2KDM4EMAPTHTR1A | |
| SCHEMBL3599366 | 0.67 | RXRA (0.41) | ALDH1A1KMT2ATDP1KDM4EMAPT | |
| SCHEMBL24117922 | 0.66 | TDP1 (0.54) | RAB9AALDH1A1MMP1MMP2MMP12 | |
| SCHEMBL9537746 | 0.65 | KMT2A (0.79) | NPC1RAB9AALDH1A1SLC6A2SLC6A3 | |
| Biphenyl SCHEMBL11403488 | 0.64 | ALDH1A1 (0.88) | NPC1RAB9AALDH1A1MGLLSLC6A2 | |
| SCHEMBL32664886 | 0.64 | RAB9A (0.75) | NPC1RAB9AALDH1A1MGLLMMP1 | |
| SCHEMBL27957337 | 0.64 | RAB9A (0.75) | NPC1RAB9AALDH1A1MGLLMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686983-B1 | USE OF PENTADIENOIC ACID DERIVATES FOR TREATEMENT OF HYPERURICEMIA | MERCK PATENT GMBH (DE) | 2007-07-11 | — | — | EP | disclosed |