Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469684 | 0.87 | PRKCZ (0.42) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL14469812 | 0.85 | KMT2A (0.38) | TDP1KMT2ASLC6A2SLC6A3ADORA2B | |
| SCHEMBL14469714 | 0.84 | TSHR (0.45) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL14469683 | 0.82 | GPBAR1 (0.40) | TDP1KMT2ASLC6A2SLC6A3TSHR | |
| SCHEMBL14469745 | 0.81 | ALDH1A1 (0.43) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL24117922 | 0.70 | TDP1 (0.54) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL30921149 | 0.67 | TDP1 (0.43) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL14031216 | 0.66 | PGR (0.40) | TDP1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL1256462 | 0.65 | ALDH1A1 (0.51) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL1400110 | 0.65 | PKM (0.37) | TSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686983-B1 | USE OF PENTADIENOIC ACID DERIVATES FOR TREATEMENT OF HYPERURICEMIA | MERCK PATENT GMBH (DE) | 2007-07-11 | — | — | EP | disclosed |