Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDXK | O00764 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30649291 | 0.88 | KDM4E (0.59) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4056862 | 0.87 | KDM4E (0.50) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3392208 | 0.79 | KDM4E (0.47) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9970098 | 0.79 | LMNA (0.71) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14899354 | 0.78 | LMNA (0.59) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| Pyridoxamine SCHEMBL30408 | 0.77 | LMNA (1.00) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11449654 | 0.77 | KDM4E (0.46) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14899377 | 0.76 | LMNA (0.56) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| Pyridoxamine SCHEMBL48103 | 0.76 | LMNA (0.96) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| Pyridoxamine SCHEMBL7749395 | 0.76 | LMNA (0.96) | LMNAKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431712-B2 | Methods for the synthesis of pyridoxamine | NEPHROGENEX, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20070161678-A1 | Methods for the synthesis of pyridoxamine | BIOSTRATUM, INC. | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161678-A1 | Methods for the synthesis of pyridoxamine | AGER, PDXK, PNPO | LMNA 855/4885KDM4E 229/4885ALDH1A1 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.