Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PDXK | O00764 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30649291 | 0.88 | KDM4E (0.59) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL14469765 | 0.87 | LMNA (0.63) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL11449654 | 0.83 | KDM4E (0.46) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL4276650 | 0.79 | KDM4E (0.47) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL3443072 | 0.77 | KDM4E (0.76) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL4224165 | 0.77 | DPP4 (0.36) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL3392208 | 0.75 | KDM4E (0.47) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL4056857 | 0.74 | NNMT (0.46) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL3442533 | 0.73 | NOS3 (0.41) | KDM4ELMNAMAPT | |
| SCHEMBL31992 | 0.72 | KDM4E (0.44) | KDM4ELMNAALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824825-A4 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | MEDICURE INT INC (BB) | 2009-07-08 | — | — | EP | disclosed |
| US-20080306108-A1 | Substituted Pyridoxines As Anti-Platelet Agents | MEDICURE INTERNATIONAL INC. (BB) | 2008-12-11 | — | — | US | disclosed |
| EP-1824825-A1 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | Medicure International Inc. (BB) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006045203-A1 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-04 | — | — | WO | disclosed |
| US-20060094749-A1 | Substituted pyridoxines as anti-platelet agents | MEDICURE INTERNATIONAL INC. | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306108-A1 | Substituted Pyridoxines As Anti-Platelet Agents | PNPO, GP6, PFKP | KDM4E 3605/4885LMNA 2020/4885ALDH1A1 1958/4885 |
| US-20060094749-A1 | Substituted pyridoxines as anti-platelet agents | PNPO, GP6, PFKP | KDM4E 3605/4885LMNA 2020/4885ALDH1A1 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.