Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.53 |
| ▸ | GNG2 | P59768 | 1/20 | 0.50 |
| ▸ | GNB1 | P62873 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | DHFR | P00374 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14477013 | 0.89 | MEN1 (0.49) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL14477011 | 0.89 | FTO (0.68) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL14477021 | 0.88 | GNG2 (0.51) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL14477019 | 0.87 | GNG2 (0.65) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL12464183 | 0.86 | MAPT (0.51) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL19657379 | 0.85 | CYP3A4 (0.45) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL14477005 | 0.83 | FTO (0.65) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL29583321 | 0.81 | FTO (0.62) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL21708060 | 0.81 | FTO (0.62) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL8918610 | 0.80 | FTO (0.69) | MAPTMEN1KMT2AFTOTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11191850-B2 | Molecular probes for detection and imaging of pancreatic cancer | PORTLAND STATE UNIVERSITY (US) | 2021-12-07 | — | — | US | disclosed |
| EP-3464293-B1 | MOLECULAR PROBES FOR DETECTION AND IMAGING OF PANCREATIC CANCER | UNIV PORTLAND STATE (US) | 2021-06-23 | — | — | EP | disclosed |
| US-20200330612-A1 | MOLECULAR PROBES FOR DETECTION AND IMAGING OF PANCREATIC CANCER | PORTLAND STATE UNIVERSITY (US) | 2020-10-22 | — | — | US | disclosed |
| US-9958451-B2 | Near-infrared fluorescent dyes with large stokes shifts | PORTLAND STATE UNIVERSITY (US) | 2018-05-01 | — | — | US | disclosed |
| US-9958451-B2 | Near-infrared fluorescent dyes with large stokes shifts | PORTLAND STATE UNIVERSITY (US) | 2018-05-01 | — | — | US | disclosed |
| WO-2017205350-A1 | MOLECULAR PROBES FOR DETECTION AND IMAGING OF PANCREATIC CANCER | PORTLAND STATE UNIVERSITY (US) | 2017-11-30 | — | — | WO | disclosed |
| US-20160154001-A1 | NEAR-INFRARED FLUORESCENT DYES WITH LARGE STOKES SHIFTS | PORTLAND STATE UNIVERSITY (US) | 2016-06-02 | — | — | US | disclosed |
| US-20160154001-A1 | NEAR-INFRARED FLUORESCENT DYES WITH LARGE STOKES SHIFTS | PORTLAND STATE UNIVERSITY (US) | 2016-06-02 | — | — | US | disclosed |
| US-9250246-B2 | Near-infrared fluorescent dyes with large stokes shifts | PORTLAND STATE UNIVERSITY (US) | 2016-02-02 | — | — | US | disclosed |
| US-9250246-B2 | Near-infrared fluorescent dyes with large stokes shifts | PORTLAND STATE UNIVERSITY (US) | 2016-02-02 | — | — | US | disclosed |
| US-20140120628-A1 | NEAR-INFRARED FLUORESCENT DYES WITH LARGE STOKES SHIFTS | THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2014-05-01 | — | — | US | disclosed |
| US-20140120628-A1 | NEAR-INFRARED FLUORESCENT DYES WITH LARGE STOKES SHIFTS | THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2014-05-01 | — | — | US | disclosed |
| WO-2013003815-A2 | NEAR-INFRARED FLUORESCENT DYES WITH LARGE STOKES SHIFTS | THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2013-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200330612-A1 | MOLECULAR PROBES FOR DETECTION AND IMAGING OF PANCREATIC CANCER | RNASE1, AMY2A, ANXA4 | MAPT 4540/4885MEN1 1072/4885KMT2A 2406/4885 |
| US-11191850-B2 | Molecular probes for detection and imaging of pancreatic cancer | RNASE1, AMY2A, ANXA4 | MAPT 4540/4885MEN1 1072/4885KMT2A 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.