Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | PAICS | P22234 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14477654 | 0.95 | CXCR4 (0.46) | SIGMAR1LMNACXCR4MEN1CHRM2 | |
| SCHEMBL14477671 | 0.89 | SIGMAR1 (0.43) | SIGMAR1MEN1CHRM2BLMKMT2A | |
| SCHEMBL14478352 | 0.88 | SIGMAR1 (0.53) | SIGMAR1LMNACXCR4MEN1CHRM2 | |
| SCHEMBL14477662 | 0.85 | SIGMAR1 (0.41) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL14477657 | 0.84 | CXCR4 (0.56) | LMNACXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL14477643 | 0.83 | GRIN1 (0.37) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL19598843 | 0.83 | CHRM5 (0.38) | SIGMAR1MEN1KMT2A | |
| SCHEMBL14478353 | 0.82 | CXCR4 (0.57) | SIGMAR1LMNACXCR4MEN1CHRM2 | |
| SCHEMBL8655258 | 0.80 | LMNA (0.59) | SIGMAR1LMNAHRH3ALDH1A1HDAC1 | |
| SCHEMBL16656260 | 0.80 | LMNA (0.59) | SIGMAR1LMNAHRH3ALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079867-B2 | Polyazamacrocyclic compound, and a production method and a biomedical use therefor | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2015-07-14 | — | — | US | disclosed |
| US-20130004423-A1 | POLYAZAMACROCYCLIC COMPOUND, AND A PRODUCTION METHOD AND A BIOMEDICAL USE THEREFOR | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004423-A1 | POLYAZAMACROCYCLIC COMPOUND, AND A PRODUCTION METHOD AND A BIOMEDICAL USE THEREFOR | SLC39A11, VIP, PBDC1 | SIGMAR1 3337/4885LMNA 1759/4885CXCR4 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.