SCHEMBL16656265

SCHEMBL16656265

O=C(O)CN1CCN(CC(=O)O)CCN(Cc2ccc(N=C=S)cc2)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 1/20 0.48
GRIN2A Q12879 1/20 0.48
GRIN2B Q13224 1/20 0.48
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 1/20 0.46
P2RY6 Q15077 1/20 0.45
CHRM1 P11229 1/20 0.44
OPRD1 P41143 1/20 0.42
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
ALOX12 P18054 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP2C19 P33261 1/20 0.41
HDAC4 P56524 1/20 0.40
KCNH2 Q12809 1/20 0.40
HDAC1 Q13547 1/20 0.40
DRD4 P21917 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8038145 1.00 GRIN1 (0.48) GRIN1GRIN2AGRIN2BALDH1A1HSD17B10
SCHEMBL14312212 0.92 SIGMAR1 (0.46) GRIN1GRIN2AGRIN2BALDH1A1HSD17B10
SCHEMBL14312255 0.87 CXCR4 (0.50) GRIN1GRIN2AGRIN2BCHRM1OPRD1
SCHEMBL8654441 0.86 CYP2D6 (0.54) GRIN1GRIN2AGRIN2BHSD17B10P2RY6
SCHEMBL887952 0.84 OPRD1 (0.47) ALDH1A1OPRD1CYP3A4CYP2D6MAPT
SCHEMBL22297856 0.84 ALDH1A1 (0.49) ALDH1A1CYP3A4CYP2D6MAPTMAPK1
SCHEMBL24728935 0.83 HTT (0.49) GRIN1GRIN2AGRIN2BALDH1A1LMNA
SCHEMBL9707222 0.83 GRIN1 (0.57) GRIN1GRIN2AGRIN2BHSD17B10P2RY6
SCHEMBL14477643 0.83 GRIN1 (0.37) GRIN1GRIN2AGRIN2BALDH1A1HSD17B10
SCHEMBL17029293 0.82 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP2D6MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642489-A1 CONJUGATE AND USES THEREOF Full-Life Technologies HK Limited (HK) 2025-11-05 EP claimed
WO-2025137443-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING SOMATOSTATIN RECEPTORS AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO claimed
WO-2025137441-A1 RADIOPHARMACEUTICALS TARGETING SOMATOSTATIN RECEPTOR 2 AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO claimed
WO-2024140670-A1 CONJUGATE AND USES THEREOF FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2024-07-04 WO claimed
CN-113730606-B CYP1B1 enzyme-targeted NIR/PET bimodal probe precursor and preparation and application thereof 上海交通大学 2022-06-28 CN claimed
CN-106573959-B Modified cyclic pentapeptides and uses thereof 慕尼黑工业大学 2022-03-25 CN claimed
CN-122075404-A Liquid formulations and methods for inhibiting pentetic acid degradation 2026-05-26 CN disclosed
US-20260124327-A1 Compounds Targeting Carbonic Anhydrase IX and Uses Thereof RAYZEBIO, INC. (US) 2026-05-07 US disclosed
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 EP disclosed
EP-4705299-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF Rayzebio, Inc. (US) 2026-03-11 EP disclosed
EP-4642489-A1 CONJUGATE AND USES THEREOF Full-Life Technologies HK Limited (HK) 2025-11-05 EP disclosed
WO-2024254339-A9 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2025-10-16 WO disclosed
EP-4594337-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING EPHRIN TYPE-A RECEPTOR 2 AND USES THEREOF Rayzebio, Inc. (US) 2025-08-06 EP disclosed
WO-2021255282-A1 CONJUGATED AND LABELLED APELIN, PREPARATION AND USES THEREOF UNIVERSITE D'AIX MARSEILLE (FR) 2021-12-23 WO disclosed
EP-3152226-B1 MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF UNIV MUENCHEN TECH (DE) 2019-05-29 EP disclosed
WO-2018154034-A1 RADIOLABELED SOLUBLE CD146, PREPARATION AND USES THEREOF UNIVERSITE D'AIX-MARSEILLE (FR) 2018-08-30 WO disclosed
EP-3152226-A1 MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF Technische Universität München (DE) 2017-04-12 EP disclosed
WO-2015185162-A1 MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF Technische Universität München (DE) 2015-12-10 WO disclosed
US-9012604-B2 Triazanonane derivatives or pharmaceutically acceptable salt thereof for enhanced fluorine-18 labeling Snur & DB Foundation (KR) 2015-04-21 US disclosed
US-9012604-B2 Triazanonane derivatives or pharmaceutically acceptable salt thereof for enhanced fluorine-18 labeling Snur & DB Foundation (KR) 2015-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124327-A1 Compounds Targeting Carbonic Anhydrase IX and Uses Thereof CA9, CA13, CA4 GRIN1 3833/4885GRIN2A 4240/4885GRIN2B 3623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.