Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18872669 | 1.00 | LMNA (0.59) | LMNAALDH1A1SIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL16656260 | 1.00 | LMNA (0.59) | LMNAALDH1A1SIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL3897416 | 0.93 | ALDH1A1 (0.64) | LMNAALDH1A1SIGMAR1HDAC1HRH3 | |
| SCHEMBL14478352 | 0.91 | SIGMAR1 (0.53) | LMNAALDH1A1SIGMAR1HDAC1HRH3 | |
| Tetraxetan SCHEMBL861961 | 0.89 | SLC6A9 (0.49) | LMNAALDH1A1SIGMAR1MAPTSLC6A9 | |
| SCHEMBL14049579 | 0.87 | SIGMAR1 (0.52) | LMNAALDH1A1SIGMAR1 | |
| SCHEMBL14478353 | 0.85 | CXCR4 (0.57) | LMNAALDH1A1SIGMAR1HRH3 | |
| SCHEMBL9610969 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SIGMAR1CYP3A4CYP2D6MAPT | |
| SCHEMBL8510915 | 0.84 | ITGB3 (0.56) | LMNAALDH1A1SIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL7556163 | 0.84 | SIGMAR1 (0.65) | ALDH1A1SIGMAR1DRD4SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2831073-B2 | — | — | 1998-12-02 | — | — | JP | claimed |
| EP-0292689-B1 | Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs | BRACCO INT BV (NL) | 1996-07-31 | — | — | EP | claimed |
| EP-0353450-B1 | Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates | DOW CHEMICAL CO (US) | 1995-03-29 | — | — | EP | claimed |
| EP-0420942-A1 | MACROCYCLIC BIFUNCTIONAL CHELANTS, COMPLEXES THEREOF AND THEIR ANTIBODY CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1991-04-10 | — | — | EP | claimed |
| WO-1989012631-A1 | MACROCYCLIC BIFUNCTIONAL CHELANTS, COMPLEXES THEREOF AND THEIR ANTIBODY CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-28 | — | — | WO | claimed |
| EP-0292689-A2 | Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs | BRACCO INTERNATIONAL B.V. (NL) | 1988-11-30 | — | — | EP | claimed |
| US-11167050-B2 | Metal complex forming compound, metal complex compound formed thereof, radioactive drug containing the metal complex compound, and method of using and preparing the metal complex compound | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2021-11-09 | — | — | US | disclosed |
| US-20200268913-A1 | RADIOACTIVE DRUG | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2020-08-27 | — | — | US | disclosed |
| US-5756065-A | DIAGNOSTIC CHELATES FOR ANTIBODIES AND RADIOACTIVE MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| US-5652361-A | ANTITUMOR | THE DOW CHEMICAL COMPANY (US) | 1997-07-29 | — | — | US | disclosed |
| US-5435990-A | Chelate-antibody complexes, treatment and diagnosis of cancer, tetraazacyclododecane compounds | THE DOW CHEMICAL COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0353450-B1 | Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates | DOW CHEMICAL CO (US) | 1995-03-29 | — | — | EP | disclosed |
| EP-0420942-A1 | MACROCYCLIC BIFUNCTIONAL CHELANTS, COMPLEXES THEREOF AND THEIR ANTIBODY CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0353450-A1 | Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates | THE DOW CHEMICAL COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |
| WO-1989012631-A1 | MACROCYCLIC BIFUNCTIONAL CHELANTS, COMPLEXES THEREOF AND THEIR ANTIBODY CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11167050-B2 | Metal complex forming compound, metal complex compound formed thereof, radioactive drug containing the metal complex compound, and method of using and preparing the metal complex compound | SLC30A6, AP1M1, SLC39A11 | LMNA 4134/4885ALDH1A1 2653/4885SIGMAR1 3243/4885 |
| US-20200268913-A1 | RADIOACTIVE DRUG | TFRC, LUC7L2, MRPL19 | LMNA 4363/4885ALDH1A1 1326/4885SIGMAR1 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.