Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.40 |
| ▸ | APC | P25054 | 3/20 | 0.40 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478087 | 0.88 | APC (0.43) | MMEFOLH1PTPN1KEAP1APC | |
| SCHEMBL14478093 | 0.83 | APC (0.44) | MMEFOLH1KEAP1APCCTNNB1 | |
| SCHEMBL14478152 | 0.83 | APC (0.51) | MMEFOLH1APC | |
| SCHEMBL14478149 | 0.78 | APC (0.54) | MMEPTPN1KEAP1APC | |
| SCHEMBL14478126 | 0.77 | APC (0.42) | FOLH1PTPN1KEAP1APCCTSS | |
| SCHEMBL14478103 | 0.76 | APC (0.60) | APC | |
| SCHEMBL14478119 | 0.75 | CCKBR (0.57) | — | |
| SCHEMBL6804098 | 0.73 | PTPN1 (0.65) | FOLH1PTPN1 | |
| SCHEMBL14478092 | 0.71 | CCKBR (0.47) | KEAP1CTNNB1 | |
| SCHEMBL31098846 | 0.71 | FKBP4 (0.51) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013001297-A1 | BINDING INHIBITORS OF THE BETA.TRANSDUCIN REPEAT - CONTAINING PROTEIN | ITI SCOTLAND LIMITED (GB) | 2013-01-03 | — | — | WO | disclosed |