Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478648 | 0.87 | ACVR1 (0.41) | MEN1KMT2APDGFRBPDGFRASMN1; SMN2 | |
| SCHEMBL14478635 | 0.85 | KDM4E (0.35) | MEN1KMT2APDGFRBPDGFRASMN1; SMN2 | |
| SCHEMBL14478619 | 0.83 | MAPK10 (0.41) | PDGFRBPDGFRAMAP4K4MAPK8CLK2 | |
| SCHEMBL14478693 | 0.74 | DHFR (0.39) | PLK4AURKAJAK2ROCK2PRKD3 | |
| SCHEMBL14478661 | 0.72 | PDGFRB (0.44) | PDGFRBPDGFRANPC1RAB9AKDR | |
| SCHEMBL14478654 | 0.71 | KDM4E (0.38) | PDGFRBPDGFRASMN1; SMN2NPC1RAB9A | |
| SCHEMBL14478674 | 0.70 | KDM4E (0.40) | MEN1KMT2APDGFRBPDGFRASMN1; SMN2 | |
| SCHEMBL14478662 | 0.69 | PDGFRB (0.45) | PDGFRBPDGFRAMAPK8KDM4EMAPK9 | |
| SCHEMBL14478621 | 0.69 | L3MBTL1 (0.39) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL14478634 | 0.68 | KDM4E (0.36) | MEN1KMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8986855-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-03-24 | — | — | US | disclosed |
| US-8986855-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-03-24 | — | — | US | disclosed |
| US-8951649-B2 | — | — | 2015-02-10 | — | — | US | disclosed |
| US-8951649-B2 | — | — | 2015-02-10 | — | — | US | disclosed |
| US-20130001529-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2013-01-03 | — | — | US | disclosed |
| US-20130001529-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130001529-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, ORC3, NR2E3 | MEN1 358/4885KMT2A 1554/4885PDGFRB 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.