Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 6/20 | 0.76 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.60 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.57 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.57 |
| ▸ | TYK2 | P29597 | 3/20 | 0.57 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.57 |
| ▸ | STK16 | O75716 | 2/20 | 0.57 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.57 |
| ▸ | BMP2K | Q9NSY1 | 2/20 | 0.57 |
| ▸ | CSF1R | P07333 | 2/20 | 0.57 |
| ▸ | ULK3 | Q6PHR2 | 2/20 | 0.57 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.55 |
| ▸ | NUAK2 | Q9H093 | 2/20 | 0.55 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 5/20 | 0.53 |
| ▸ | KDR | P35968 | 5/20 | 0.53 |
| ▸ | CDK2 | P24941 | 4/20 | 0.53 |
| ▸ | CDK4 | P11802 | 2/20 | 0.53 |
| ▸ | CDK7 | P50613 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853368 | 0.87 | PTK2 (1.00) | PTK2NTRK1CA2AAK1TBK1 | |
| SCHEMBL1627982 | 0.87 | PTK2 (1.00) | PTK2NTRK1CA2AAK1TBK1 | |
| SCHEMBL29853323 | 0.83 | PTK2 (1.00) | PTK2NTRK1CA2AAK1TBK1 | |
| SCHEMBL1628120 | 0.83 | PTK2 (1.00) | PTK2NTRK1CA2AAK1TBK1 | |
| SCHEMBL4062155 | 0.80 | PTK2 (0.68) | PTK2NTRK1CA2AAK1TBK1 | |
| SCHEMBL4066898 | 0.79 | PTK2 (0.67) | PTK2NTRK1CA2AAK1TBK1 | |
| SCHEMBL4057837 | 0.79 | PTK2 (0.67) | PTK2NTRK1CA2AAK1TBK1 | |
| SCHEMBL4065848 | 0.76 | CA2 (0.64) | PTK2NTRK1CA2AAK1TBK1 | |
| SCHEMBL28713120 | 0.76 | NTRK1 (1.00) | PTK2NTRK1AURKANTRK3NTRK2 | |
| SCHEMBL4063385 | 0.75 | CA2 (1.00) | PTK2NTRK1CA2TYK2MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130005964-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | PFIZER, INC. | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005964-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | GPR119, INSR, LYAR | PTK2 4052/4885NTRK1 4159/4885CA2 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.