Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | DNM1L | O00429 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18573457 | 0.88 | PTPN1 (0.63) | PTPN1SLC6A3KCNH2TAAR1NPC1 | |
| SCHEMBL6246566 | 0.84 | PLA2G10 (0.59) | PLA2G10NPC1RAB9ASMN1; SMN2POLQ | |
| SCHEMBL18573582 | 0.84 | PTPN1 (0.63) | PTPN1SLC6A3KCNH2TAAR1NPC1 | |
| SCHEMBL21653091 | 0.81 | DNM1L (0.46) | PTPN1DNM1LPLA2G10NPC1RAB9A | |
| SCHEMBL12789568 | 0.77 | PTPN1 (0.84) | PTPN1SLC6A3KCNH2TAAR1NPC1 | |
| SCHEMBL31337446 | 0.75 | PTPN1 (0.67) | PTPN1SLC6A3KCNH2TAAR1NPC1 | |
| SCHEMBL976455 | 0.70 | CDC7 (0.57) | DNM1LPLA2G10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12790020 | 0.70 | SMN1; SMN2 (0.67) | PTPN1SLC6A3KCNH2TAAR1NPC1 | |
| SCHEMBL991022 | 0.70 | NOTUM (0.70) | NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL12789206 | 0.69 | PTPN1 (0.70) | PTPN1SLC6A3KCNH2TAAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200046-B2 | Reporter system for high throughput screening of compounds and uses thereof | CORNELL UNIVERSITY (US) | 2015-12-01 | — | — | US | disclosed |
| US-20130005666-A1 | REPORTER SYSTEM FOR HIGH THROUGHPUT SCREENING OF COMPOUNDS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005666-A1 | REPORTER SYSTEM FOR HIGH THROUGHPUT SCREENING OF COMPOUNDS AND USES THEREOF | NFE2, NFE2L2, UBE2N | PTPN1 4679/4885DNM1L 862/4885SLC6A3 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.