Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14479883 | 0.84 | PTPN1 (0.60) | PLA2G10RAB9ANPC1SMN1; SMN2POLQ | |
| SCHEMBL23035052 | 0.80 | HDAC1 (0.57) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1328083 | 0.75 | PLA2G10 (0.60) | PLA2G10RAB9ANPC1CLK1SMN1; SMN2 | |
| SCHEMBL1328163 | 0.74 | PLA2G10 (1.00) | PLA2G10RAB9ANPC1CLK1SMN1; SMN2 | |
| SCHEMBL21653091 | 0.74 | DNM1L (0.46) | PLA2G10RAB9ANPC1CLK1SMN1; SMN2 | |
| SCHEMBL15999120 | 0.72 | PLA2G10 (0.56) | PLA2G10RAB9ANPC1DYRK1APRKAB2 | |
| SCHEMBL16702935 | 0.71 | SMN1; SMN2 (0.47) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18573457 | 0.70 | PTPN1 (0.63) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5041568 | 0.70 | SMN1; SMN2 (0.54) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL24499935 | 0.69 | PLA2G10 (0.59) | PLA2G10RAB9ANPC1CLK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030206-A1 | ARYL-1,3-AZOLE DERIVATIVES AND METHODS FOR INHIBITING HEPARNASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-04-07 | — | — | WO | disclosed |