Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344604 | 0.89 | MAPT (0.53) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5333962 | 0.85 | LMNA (0.53) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL14484090 | 0.83 | RAB9A (0.53) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5337496 | 0.79 | MAPT (0.58) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5341731 | 0.76 | HSD11B1 (0.53) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5334463 | 0.72 | GAA (0.45) | KMT2AMEN1MAPTRAB9AALDH1A1 | |
| SCHEMBL12218424 | 0.70 | KMT2A (0.67) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5337736 | 0.70 | HSD11B1 (0.51) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL13333003 | 0.69 | CNR1 (0.46) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5340796 | 0.68 | RAB9A (0.53) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230020-B2 | 11β-hydroxysteroid dehydrogenase inhibitors | STERIX LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7230020-B2 | 11β-hydroxysteroid dehydrogenase inhibitors | STERIX LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |