Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13333001 | 0.81 | CNR2 (0.48) | CNR1CNR2ALDH1A1LMNANPC1 | |
| SCHEMBL13361615 | 0.76 | CNR1 (0.43) | CNR1CNR2ALDH1A1LMNANPSR1 | |
| SCHEMBL5344604 | 0.72 | MAPT (0.53) | ALDH1A1LMNAHSD11B1MEN1KMT2A | |
| SCHEMBL5337736 | 0.71 | HSD11B1 (0.51) | ALDH1A1LMNAHSD11B1MEN1KMT2A | |
| SCHEMBL5334463 | 0.70 | GAA (0.45) | ALDH1A1HSD11B1MEN1KMT2ANPC1 | |
| SCHEMBL5340071 | 0.69 | HSD11B1 (0.59) | ALDH1A1LMNAHSD11B1MEN1KMT2A | |
| SCHEMBL14484090 | 0.69 | RAB9A (0.53) | LMNAHSD11B1MEN1KMT2ANPSR1 | |
| SCHEMBL5340796 | 0.69 | RAB9A (0.53) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL5333962 | 0.69 | LMNA (0.53) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14484121 | 0.69 | KMT2A (0.57) | ALDH1A1LMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | HSD3B1, HSD3B2, HSD11B1 | CNR1 473/4885CNR2 927/4885ALDH1A1 437/4885 |
| US-20100120789-A1 | Compound | NR0B2, NR0B1, NR4A1 | CNR1 40/4885CNR2 121/4885ALDH1A1 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.