Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | PNMT | P11086 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14555180 | 0.90 | HTR2A (0.40) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL18700448 | 0.84 | ACHE (0.38) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL19129465 | 0.79 | METAP1 (0.34) | KDM1AMETAP1 | |
| SCHEMBL14487997 | 0.78 | KDM1A (0.50) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL6015527 | 0.77 | TDP1 (0.38) | PNMTKDM1ATDP2PDK2METAP1 | |
| SCHEMBL19131082 | 0.75 | PDK2 (0.32) | PDK2METAP1 | |
| SCHEMBL15316154 | 0.72 | BACE1 (0.35) | PNMTKDM1ATDP2PDK2 | |
| SCHEMBL14521000 | 0.72 | PDK2 (0.42) | OPRM1OPRD1OPRK1KDM1ATDP2 | |
| SCHEMBL9999700 | 0.72 | ESR1 (0.45) | TDP2PDK2 | |
| SCHEMBL17961919 | 0.71 | PDK2 (0.44) | OPRM1OPRD1OPRK1PNMTKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10270037-B2 | Polymers, monomers and methods of forming polymers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2019-04-23 | — | — | US | disclosed |
| US-20170098770-A1 | POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2017-04-06 | — | — | US | disclosed |
| US-20170098770-A1 | POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2017-04-06 | — | — | US | disclosed |
| US-20170098770-A1 | POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2017-04-06 | — | — | US | disclosed |
| US-9562136-B2 | Polymers, monomers and methods of forming polymers | CAMBRIDGE DISPLAY TECHNOLOGY, LTD. (GB) | 2017-02-07 | — | — | US | disclosed |
| US-9562136-B2 | Polymers, monomers and methods of forming polymers | CAMBRIDGE DISPLAY TECHNOLOGY, LTD. (GB) | 2017-02-07 | — | — | US | disclosed |
| US-9562136-B2 | Polymers, monomers and methods of forming polymers | CAMBRIDGE DISPLAY TECHNOLOGY, LTD. (GB) | 2017-02-07 | — | — | US | disclosed |
| US-20140235800-A1 | POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20140235800-A1 | POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20140235800-A1 | POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |
| WO-2013005026-A2 | POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2013-01-10 | — | — | WO | disclosed |
| WO-2013005026-A2 | POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2013-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170098770-A1 | POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS | PCNA, PARG, PARN | HTR2A 1255/4885HTR2C 804/4885HTR2B 876/4885 |
| US-10270037-B2 | Polymers, monomers and methods of forming polymers | PCNA, PARG, PARN | HTR2A 1255/4885HTR2C 804/4885HTR2B 876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.