Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14555180 | 0.93 | HTR2A (0.40) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL14488442 | 0.84 | HTR2A (0.36) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL15316154 | 0.80 | BACE1 (0.35) | PNMT | |
| SCHEMBL13567251 | 0.75 | ALDH1A1 (0.44) | OPRK1 | |
| SCHEMBL16656146 | 0.75 | ALDH1A1 (0.42) | — | |
| SCHEMBL27043600 | 0.74 | MAPT (0.46) | ACHEOPRK1 | |
| SCHEMBL12109715 | 0.73 | PDK2 (0.41) | OPRM1OPRD1OPRK1 | |
| SCHEMBL28813511 | 0.72 | ALDH1A1 (0.38) | ACHEOPRK1 | |
| SCHEMBL15316155 | 0.71 | MAPK1 (0.48) | ACHEHTR2AHTR2C | |
| SCHEMBL19153470 | 0.71 | ACHE (0.45) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170098770-A1 | POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2017-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170098770-A1 | POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS | PCNA, PARG, PARN | ACHE 3154/4885HTR2A 1255/4885HTR2C 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.