SCHEMBL15316154

SCHEMBL15316154

Cc1ccc2c(c1)C(c1ccc3c(c1)CC3)(c1ccc3c(c1)CC3)c1cc(Br)ccc1-2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.35
APP P05067 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TDP2 O95551 1/20 0.33
MALT1 Q9UDY8 1/20 0.32
SRD5A1 P18405 2/20 0.32
SRD5A2 P31213 1/20 0.32
KDM1A O60341 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
PNMT P11086 1/20 0.32
ASIC3 Q9UHC3 1/20 0.32
TYMS P04818 1/20 0.32
PGR P06401 1/20 0.32
ALDH1A1 P00352 3/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
NFKB1 P19838 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6015527 0.91 TDP1 (0.38) BACE1APPTDP1L3MBTL1TDP2
SCHEMBL17961919 0.84 PDK2 (0.44) TDP1L3MBTL1TDP2SRD5A1SRD5A2
SCHEMBL20321461 0.82 PDK2 (0.34) MALT1SRD5A1KDM1AESR1ESR2
SCHEMBL13562939 0.82 PNMT (0.35) TDP1L3MBTL1TDP2SRD5A1SRD5A2
SCHEMBL13567251 0.81 ALDH1A1 (0.44) BACE1APPTDP2ESR1ESR2
SCHEMBL16656146 0.81 ALDH1A1 (0.42) TDP2MALT1PGRALDH1A1MAPT
SCHEMBL15138949 0.80 POLB (0.36) ALDH1A1NPC1NFKB1RAB9ANFKB2
SCHEMBL18700448 0.80 ACHE (0.38) PNMT
SCHEMBL18347142 0.79 TDP1 (0.42) BACE1APPTDP1L3MBTL1KDM1A
SCHEMBL18563546 0.79 TDP2 (0.39) TDP1L3MBTL1TDP2SRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9793486-B2 Polymer compound and light-emitting element using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-17 US disclosed
US-9269905-B2 Polymer compound having carbon cluster structure and organic device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-02-23 US disclosed
US-20140014935-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 US disclosed
US-20130270545-A1 POLYMER COMPOUND HAVING CARBON CLUSTER STRUCTURE AND ORGANIC DEVICE USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-17 US disclosed