Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605742 | 0.85 | HTR2A (0.45) | NPY5RSIGMAR1HTR1ANQO2MTNR1A | |
| SCHEMBL1346063 | 0.82 | NQO2 (0.48) | NPY5RSIGMAR1HTR1ANQO2MTNR1A | |
| SCHEMBL607858 | 0.81 | MTNR1A (0.48) | NPY5RNQO2MTNR1AMTNR1B | |
| SCHEMBL611892 | 0.80 | SIGMAR1 (0.47) | SIGMAR1HTR1AOPRM1OPRD1SLC6A2 | |
| SCHEMBL1346374 | 0.79 | NQO2 (0.48) | NPY5RSIGMAR1HTR1ANQO2MTNR1A | |
| SCHEMBL13151461 | 0.78 | NPY5R (0.62) | NPY5RSIGMAR1HTR1A | |
| SCHEMBL14489391 | 0.78 | OPRM1 (0.44) | SIGMAR1HTR1ANQO2MTNR1AMTNR1B | |
| SCHEMBL16652424 | 0.77 | SLC6A9 (0.53) | NPY5RSIGMAR1HTR1AHTR2A | |
| SCHEMBL14957577 | 0.77 | SLC6A9 (0.53) | NPY5RSIGMAR1HTR1AHTR2A | |
| SCHEMBL603655 | 0.77 | ATM (0.45) | NPY5RNQO2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007073503-A2 | INDANE MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-KB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-28 | — | — | WO | disclosed |