Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 18/20 | 0.47 |
| ▸ | THRA | P10827 | 17/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5407993 | 0.92 | THRB (0.55) | THRBTHRA | |
| SCHEMBL14489394 | 0.87 | THRB (0.56) | THRBTHRA | |
| SCHEMBL14489277 | 0.86 | THRB (0.48) | THRBTHRA | |
| SCHEMBL14489314 | 0.85 | THRA (0.66) | THRBTHRA | |
| SCHEMBL5392071 | 0.82 | THRA (0.63) | THRBTHRA | |
| SCHEMBL14489170 | 0.81 | THRB (0.66) | THRBTHRA | |
| SCHEMBL14489354 | 0.81 | THRB (0.66) | THRBTHRA | |
| SCHEMBL14489475 | 0.81 | THRA (0.68) | THRBTHRA | |
| SCHEMBL14489221 | 0.81 | THRB (0.61) | THRBTHRA | |
| SCHEMBL5391484 | 0.80 | THRB (0.70) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230031-B2 | Thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230031-B2 | Thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-06-12 | — | — | US | disclosed |