Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23811151 | 0.79 | SMN1; SMN2 (0.41) | POLBALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL4404816 | 0.79 | XPO1 (0.33) | — | |
| SCHEMBL21389800 | 0.75 | TDP1 (0.32) | TDP1 | |
| SCHEMBL9064507 | 0.74 | CSNK2A2 (0.46) | POLBALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL14493740 | 0.74 | TSHR (0.32) | — | |
| SCHEMBL8889957 | 0.72 | JUN (0.33) | — | |
| SCHEMBL4841161 | 0.72 | GSK3A (0.31) | — | |
| SCHEMBL5599723 | 0.72 | XPO1 (0.30) | — | |
| SCHEMBL20880328 | 0.72 | POLB (0.48) | POLBALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL209740 | 0.72 | MGLL (0.44) | ALDH1A1HTTSMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070141021-A1 | Methylmaleimidyl polymer derivatives | SUN BIO, INC. | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070141021-A1 | Methylmaleimidyl polymer derivatives | MMAB, CMBL, MGAM | POLB 1371/4885ALDH1A1 3215/4885KDM4E 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.