Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208484 | 0.88 | PPARD (0.43) | PPARDPPARAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL4754624 | 0.88 | PPARD (0.43) | PPARDPPARAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL209669 | 0.74 | MEN1 (0.45) | L3MBTL1ALDH1A1MAPTNPBWR1MCHR1 | |
| SCHEMBL210615 | 0.73 | KDM4E (0.44) | L3MBTL1ALDH1A1MAPTNPBWR1MCHR1 | |
| SCHEMBL207969 | 0.72 | AURKA (0.46) | L3MBTL1ALDH1A1MAPTNPBWR1MCHR1 | |
| SCHEMBL209309 | 0.72 | TRPV6 (0.41) | L3MBTL1ALDH1A1MAPTNPBWR1MCHR1 | |
| SCHEMBL208548 | 0.71 | POLB (0.53) | L3MBTL1ALDH1A1MAPTNPBWR1MCHR1 | |
| SCHEMBL2731281 | 0.71 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1MAPTNPBWR1MCHR1 | |
| SCHEMBL208834 | 0.71 | OPRM1 (0.48) | L3MBTL1ALDH1A1MAPTNPBWR1MCHR1 | |
| SCHEMBL209448 | 0.70 | POLB (0.52) | L3MBTL1ALDH1A1MAPTNPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072017-A2 | ENZYME INHIBITORS | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-06-28 | — | — | WO | disclosed |