Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496263 | 0.92 | ALOX15 (0.40) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL377313 | 0.91 | NPSR1 (0.41) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL15483848 | 0.90 | TDP1 (0.46) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL8765490 | 0.82 | TDP1 (0.38) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL15483569 | 0.82 | SMN1; SMN2 (0.37) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL11938344 | 0.82 | SMN1; SMN2 (0.54) | TDP1MAPTKDM4EKMT2A | |
| SCHEMBL522437 | 0.81 | GRIN2D (0.44) | TDP1TSHRNPSR1GRIN2DGRIN3B | |
| SCHEMBL6161950 | 0.81 | TDP1 (0.37) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL23568184 | 0.80 | KDM4E (0.50) | TDP1ALOX15TSHRKDM4ELMNA | |
| SCHEMBL15483873 | 0.79 | PPARG (0.48) | TDP1ALOX15TSHRCYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229842-B2 | Metal chelate containing compositions for use in chemiluminescent assays | DADE BEHRING MARBURG GMBH (DE) | 2007-06-12 | — | — | US | disclosed |
| US-7229842-B2 | Metal chelate containing compositions for use in chemiluminescent assays | DADE BEHRING MARBURG GMBH (DE) | 2007-06-12 | — | — | US | disclosed |