Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | EYA2 | O00167 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765490 | 0.98 | TDP1 (0.38) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL14496263 | 0.90 | ALOX15 (0.40) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL11303061 | 0.89 | AOC3 (0.36) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL377313 | 0.89 | NPSR1 (0.41) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL13997749 | 0.87 | LTB4R (0.39) | PPARGPPARAKDM4EMEN1RAB9A | |
| SCHEMBL23627732 | 0.85 | MEP1B (0.38) | HDAC1HDAC2KDM4EEPORMEN1 | |
| SCHEMBL13492109 | 0.85 | SMPD2 (0.36) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL13997750 | 0.84 | LTB4R (0.41) | AOC3PPARGPPARAHDAC1KDM4E | |
| SCHEMBL9594349 | 0.84 | LTB4R (0.41) | AOC3PPARGPPARAHDAC1KDM4E | |
| SCHEMBL9594479 | 0.83 | MCL1 (0.37) | AOC3PPARGPPARAHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770610-B1 | Biospecific binding reactants labelled with luminescent lanthanide chelates and their use | WALLAC OY (FI) | 2005-07-06 | — | — | EP | disclosed |
| EP-0770610-A1 | Biospecific binding reactants labelled with luminescent lanthanide chelates and their use | WALLAC OY (FI) | 1997-05-02 | — | — | EP | disclosed |
| EP-0403593-B1 | TERPYRIDINE DERIVATIVES | WALLAC OY (FI) | 1997-03-19 | — | — | EP | disclosed |
| US-5324825-A | Terpyridine derivatives | WALLAC OY (FI) | 1994-06-28 | — | — | US | disclosed |
| US-5202423-A | Terpyridine derivatives | WALLAC OY | 1993-04-13 | — | — | US | disclosed |